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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.26%⁩, the S&P 500 down ⁦0.44%⁩, and the Nasdaq Composite down ⁦0.90%⁩. Market breadth is negative, with 3,609 stocks declining versus 1,501 advancing, pointing to a broadly bearish bias.

Dow Jones
52,254.1
Change
-135.65-0.26%
S&P 500
7,517.04
Change
-32.9-0.44%
Nasdaq Composite
25,024.701
Change
-228.438-0.90%
24H Gainers
1,501
24H Losers
3,609

52 Week Gainers

#Stock52 Week Range
4401Aware Inc.AWRE$0.89-1.57%32.67K$19.40M$0.82 - $2.570.00%
4402Sound Point Meridian Capital, Inc.SPMC$5.76+1.40%28.65K$118.16M$5.43 - $16.750.00%
4403ABVC BioPharma, Inc.ABVC$1.00-2.54%32.04K$26.64M$0.71 - $3.060.00%
4404Outset Medical, Inc.OM$4.22+2.43%169.35K$79.62M$2.84 - $12.470.00%
4405Mineralys Therapeutics, Inc.MLYS$15.54-1.83%1.46M$1.38B$14.91 - $47.650.00%
4406AEye, Inc.LIDR$0.84-5.23%472.10K$39.25M$0.76 - $3.050.00%
4407ParaZero Technologies Ltd.PRZO$0.48-1.67%115.57K$12.58M$0.38 - $1.510.00%
4408Metalpha Technology Holding LimitedMATH$0.90-10.59%36.91K$42.93M$0.73 - $3.190.00%
4409Jayud Global Logistics LimitedJYD$1.23-13.73%73.02K$3.88M$0.47 - $5.750.00%
4410Cellectar Biosciences INC NEWCLRB$1.23-3.91%61.42K$11.61M$1.11 - $4.700.00%
4411Alphatec Holdings, Inc.ATEC$7.00-5.28%3.84M$1.09B$6.81 - $23.290.00%
4412Lanvin Group Holdings LimitedLANV$0.70+1.54%10.92K$87.92M$0.63 - $2.310.00%
4413Alnylam Pharmaceuticals, Inc.ALNY$151.63-3.19%1.95M$20.31B$149.23 - $479.790.00%
4414Pyxis Oncology, Inc.PYXS$1.63-4.71%527.53K$194.44M$1.03 - $5.550.00%
4415Tvardi Therapeutics, Inc.TVRD$1.43+1.42%541.16K$19.02M$0.77 - $5.690.00%
4416Heron Therapeutics, Inc.HRTX$0.38+1.46%10.69M$71.57M$0.26 - $1.570.00%
4417Solidion Technology, Inc.STI$3.97-4.21%192.93K$35.66M$2.94 - $46.000.00%
4418Solana CompanyHSDT$1.83-4.69%745.03K$110.90M$1.19 - $5.770.00%
4419Peraso, Inc.PRSO$0.35-1.51%183.19K$5.32M$0.32 - $2.160.00%
4420MicroCloud Hologram Inc.HOLO$1.25-9.85%414.53K$17.64M$0.88 - $3.900.00%
4421Equus Total Return, Inc.EQS$0.63+23.00%3.18K$8.85M$0.52 - $2.050.00%
4422LifeMD, Inc.LFMD$1.74-17.42%2.23M$83.63M$1.71 - $5.440.03%
4423Cheche Group Inc.CCG$11.43+19.39%27.11K$22.56M$4.11 - $36.050.00%
4424HomesToLife LtdHTLM$1.08-1.73%1.92K$96.95M$1.00 - $4.190.00%
4425Nexus Advanced Technologies Inc.NXAT$0.44-3.71%31.94K$1.49M$0.33 - $1.500.00%
4426Oxford Lane Capital Corp.OXLC$5.00-1.97%2.20M$489.66M$4.62 - $15.390.00%
4427Masonglory LimitedMSGY$4.06+14.90%360.64K$7.40M$1.73 - $52.800.00%
4428Cipher Digital Inc.CIFR$6.52-4.26%31.48M$2.97B$5.07 - $30.140.00%
4429Tao Synergies Inc.TAOX$2.60-5.15%68.02K$20.93M$2.17 - $8.770.03%
4430Briacell Therapeutics Corp.BCTX$3.67+0.67%24.86K$32.09M$2.60 - $13.090.00%
4431Genelux CorporationGNLX$1.94-6.28%86.28K$87.82M$1.77 - $6.260.00%
4432IREN LimitedIREN$19.71-7.89%67.19M$7.97B$17.16 - $70.710.00%
4433Garden Stage LimitedGSIW$10.64+3.54%1.76K$15.11M$8.00 - $38.550.00%
4434Metagenomi Therapeutics, Inc.MGX$0.70-0.83%147.98K$26.52M$0.60 - $2.270.00%
4435Bragg Gaming Group Inc.BRAG$0.69+4.35%112.30K$21.03M$0.63 - $2.740.00%
4436Hydrofarm Holdings Group, Inc.HYFM$0.73-5.99%51.99K$3.51M$0.50 - $3.200.00%
4437Akebia Therapeutics, Inc.AKBA$0.54+1.54%5.16M$150.47M$0.36 - $1.890.00%
4438Trump Media & Technology Group Corp.DJT$4.29+5.42%11.43M$1.19B$3.80 - $17.090.00%
4439Net Lease Office PropertiesNLOP$9.56+0.95%115.67K$141.70M$8.80 - $30.262.07%
4440C1 Fund Inc.CFND$2.18-2.27%18.72K$14.45M$2.04 - $7.000.00%
4441EVOGENE LTD.EVGN$0.38+30.40%2.20M$3.68M$0.25 - $1.280.00%
4442WhiteFiber, Inc.WYFI$9.21-3.81%2.00M$344.97M$7.43 - $46.870.00%
4443Neighborhood Intelligence, Inc.NXH$1.36-9.93%4.28M$133.95M$1.29 - $4.550.00%
4444Kandi Technologies Group, Inc.KNDI$3.46+0.14%4.17K$35.59M$3.22 - $12.000.00%
4445Plutus Financial Group LimitedPLUT$1.16+3.12%27.94K$17.73M$0.74 - $3.650.00%
4446ZoomInfo Technologies Inc.GTM$3.33-5.13%2.64M$978.63M$2.54 - $10.790.00%
4447Datasea Intelligent Technology LtdDTSS$0.55+1.49%16.95K$8.03M$0.52 - $2.290.00%
4448NexMetals Mining Corp.NEXM$1.22-3.10%51.18K$43.32M$1.15 - $4.710.00%
4449Solesence, Inc.SLSN$0.88-1.01%33.25K$62.45M$0.61 - $3.170.00%
4450Inseego Corp.INSG$4.24+0.47%142.30K$69.62M$3.58 - $21.900.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Aware Inc. (AWRE) currently leads with a 52-week gain of 64.94% as of 2026-11-11 01:45 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.